Search results for "Paralogous Gene"

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Network motif-based analysis of regulatory patterns in paralogous gene pairs

2020

Current high-throughput experimental techniques make it feasible to infer gene regulatory interactions at the whole-genome level with reasonably good accuracy. Such experimentally inferred regulatory networks have become available for a number of simpler model organisms such as S. cerevisiae, and others. The availability of such networks provides an opportunity to compare gene regulatory processes at the whole genome level, and in particular, to assess similarity of regulatory interactions for homologous gene pairs either from the same or from different species. We present here a new technique for analyzing the regulatory interaction neighborhoods of paralogous gene pairs. Our central focu…

0303 health sciencesGenomeGene regulatory networkComputational BiologyWhole genome duplicationSaccharomyces cerevisiaeComputational biologyParalogous GeneBiologyBiochemistryComputer Science ApplicationsEvolution Molecular03 medical and health sciencesNetwork motif0302 clinical medicineGene DuplicationEscherichia coliAnimalsGene Regulatory NetworksCaenorhabditis elegansMolecular BiologyGene030217 neurology & neurosurgeryTranscription Factors030304 developmental biologyJournal of Bioinformatics and Computational Biology
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easyPAC: A Tool for Fast Prediction, Testing and Reference Mapping of Degenerate PCR Primers from Alignments or Consensus Sequences

2012

Video abstract A video abstract by the authors of this paper is available. video-abstract8870.mov

homologous genesparalogous genesComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONlcsh:EvolutionGenomicsComputational biologyBiologyBioinformaticslaw.inventionlawDegenerate primerGeneticsConsensus sequenceSoftware Reviewlcsh:QH359-425De novo sequencingPCR primer predictionEcology Evolution Behavior and SystematicsPolymerase chain reactionSequence (medicine)Degenerate energy levelsalignmentComputer Science Applicationsconsensus sequencedegenerate primersPrimer (molecular biology)Evolutionary Bioinformatics
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